January 29th 2018
5 Important Concepts and Muddiest Points
innate immune system is present at birth, it’s fast, lacks specificity, and memory;
and as a result does not improve with each pathogen encounter.
first line of defense for innate immunity: is the skin which is typically
impermeable and the mucous membrane that prevents bacteria from sticking to the
epithelial cells, and entering the body.
compete with the normal microbiota for nutrients making it a great defense,
however any break in this defense allows for opportunistic pathogens to
infiltrate and cause harm.
peptides (AMP) are small amphipathic proteins that are essentially for fighting
an infection, however they must be activated in order to be cleaved and released.
are cytokines that are produced to inhibit the spread of a virus by signaling neighboring
cells to enter a viral resistance state.
Defensins and APOBEC3G