For analysis of QoL,
some questionnaires were developed exclusively
for patients with Parkinson’s disease (PD). The
best known are two scales, Quality of Life Questionnaire (PDQL).
Martinez-Martin believes that the quality
Parkinson’s Disease. Questionnaire (PDQ-39)
and Parkinson’s Disease of life scales are
more useful than other scales in evaluating
the results of rehabilitation and drug
treatment of Parkinson’s disease or neurosurgery 7. Hence, Parkinson’s
Disease Questionnaire- 39 is being used in this study.
Therefore, evaluation of
the severity of any disease should include not only the clinical factors but
also the psychological & social factors pertaining with the patient.
Parkinson’s Disease has a profound negative impact on the Quality of Life (QoL)
as pointed out by numerous studies, patients suffer from fatigue, dementia,
emotional problems, sleep disorders, difficulty in speech and balance,
depression, diminished cognitive functions and several other lifestyle changes
Quality of Life (QoL) is
a multi-dimensional construct, which includes at least three main domains:
physical, mental and social. In medicinal sciences, researchers and physicians
have often used health-related quality of life concept, which concentrates on
the impact of the disease and/or treatment on patients’ perception of their lifestyle
and on subjective well-being or satisfaction with life 5.
Patients are usually
treated with Levodopa, COMT Inhibitors, Dopamine Agonists, Non-Dopaminergic
Therapy, etc 3. Therefore, auditing of prescriptions related to the disease
is essential to increase the therapeutic efficacy and to decrease the side
effects & also to provide feedback to the prescribers. The main aim of
this drug utilization study is to facilitate rational drug use and knowing the
efficacy of each one of them 4.
The rampancy of the
disease ranges from 41 people per 100,000 in the fourth decade of life to more
than 1,900 people per 100,000 among those 80 and older 2.
Parkinson’s disease (PD)
is included in a group of neurodegenerative conditions called motor system diseases,
which are the result of the loss of dopaminergic brain cells. The primary
symptoms of PD are tremor, or trembling in limbs, jaw, and face rigidity, or
stiffness of the limbs and slowness of trunk movement, postural instability, or
impaired balance and coordination 1.