The purpose of this study was the engineering a
physical barrier and the construction of an active immunomodulatory motif to
induce regulatory T cells to create a tolerogenic niche for “hide” of islet
cells from the immune system as same as tumors hide themselves from immune
attack. In other word, these capsules were engineered to provide a ring of T-cells around the graft like “invisibility cloak “against the
body’s immune system cells.)

or

We Will Write a Custom Essay Specifically
For You For Only $13.90/page!


order now

The purpose of this study was synthesis the
engineered Jagged-1-conjugated microcapsules to improve immunoprotection of
pancreatic islets by impart local and direct modulation of host responses for
“hide” of islet cells from the immune system as same as tumors hide themselves
from immune attack. In other word, these capsules were engineered to provide a ring of T-cells around graft like “invisibility cloak “against the
body’s immune system cells.

This study is a new model which has targeting
the key challenges in the success of islet transplantation with the idea of a
cancer model that demonstrates the favorable effects of immune alterations in
the transplant milieu and suggests a unique strategy for minimizing systemic
immunosuppression and promoting islet allograft survival.

Written by
admin
x

Hi!
I'm Colleen!

Would you like to get a custom essay? How about receiving a customized one?

Check it out